Imagery Rescripting and Cognitive Restructuring versus Treatment-As- Usual in the treatment of mild and severe depression: a randomized controlled trial

Not Applicable

• Conditions: F33.2; F33.1; F32.2; F32.1; Recurrent depressive disorder, current episode severe without psychotic symptoms; Recurrent depressive disorder, current episode moderate; Severe depressive episode without psychotic symptoms; Moderate depressive episode

• Registration Number: DRKS00030809
• Lead Sponsor: Zentrum für Integrative Psychiatrie Kiel

Brief Summary

There was a statistically significant interaction between time and group, (Greenhouse–Geisser F(1.00, 31) = 16.29, p < .001, partielles ?² = .34.

Detailed Description

Not available

Study Timeline

• Study Completion: 2021-06-15
• Study Start: 2023-02-06
• Results First Posted: 2023-02-06
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 46

Inclusion Criteria

main diagnosis: moderate or severe depressive episode (F32.1 or F32.2) or a
recurrent depressive disorder, current episode moderate or severe (F33.1 or 33.2)
HAMD > 21 and BDI-II >19

Exclusion Criteria

Treatment by electroconvulsive therapy or intake of benzodiazepines. Serious diseases, which make a participation disproportionate (e.g. advanced tumor disease) or distort the study results (e.g. mental disability or chronic inflammatory disease) .
Patients with acute suicidality (missing capacity to consult, cognitive constraint on suicidal plans or no reason to survive)

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
In the fourth psychotherapeutic session severeness of depression will be assessed by widely known measure: Hamilton Depression Rating Scale (HDRS) to show effectiveness of preceding intervention

Secondary Outcome Measures

Name	Time	Method
In the fourth psychotherapeutic session severeness of depression will be assessed by widely known self report measure: Beck-Depression-Inventory-II ; BDI-II) to show effectiveness of preceding intervention.<br>Additionally assessment of daily step count will be executed to gain a correlate of severeness of depression