Effect of Sevoflurane and Propofol on the Optic Nerve Sheath Diameter

Completed

• Conditions: Optic Nerve Sheath Diameter
• Interventions: Diagnostic Test: Ultrasound examination of the optic nerve sheath diameter

• Registration Number: NCT04955925
• Lead Sponsor: SMG-SNU Boramae Medical Center

Brief Summary

In the present study, we compare the effect of sevoflurane and propofol on the optic nerve sheath diameter in patients undergoing middle ear surgery.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2021-03-31
• Study First Submitted QC: 2021-07-06
• Study First Posted: 2021-07-09
• Study Start: 2021-07-26
• Primary Completion: 2022-08-18
• Study Completion: 2022-08-18
• Status Verified: 2023-03
• Last Update Submitted: 2023-03-15
• Last Update Posted: 2023-03-17

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 58

Inclusion Criteria

• Patients undergoing middle ear surgery

Exclusion Criteria

• History of cerebrovascular diseases
• Increased intracranial pressure
• History of ophthalmic surgery or diseases

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Propofol group	Ultrasound examination of the optic nerve sheath diameter	Anesthesia is maintained with total venous anesthesia using propofol during the surgery.
Sevoflurane group	Ultrasound examination of the optic nerve sheath diameter	Anesthesia is maintained with sevoflurane during the surgery.

Primary Outcome Measures

Name	Time	Method
Change of the optic nerve sheath diameter	At 1 minute after the induction of anesthesia and at 1 minute after the end of surgery	The optic nerve sheath of each eye is observed using ultrasound, and the optic nerve sheath diameter is assessed after induction of anesthesia and at the end of surgery.

Secondary Outcome Measures

Name	Time	Method
Optic nerve sheath diameter at each time point	At 1 minute after the induction of anesthesia and at 1 minute after the end of surgery	The optic nerve sheath of each eye is observed using ultrasound, and the optic nerve sheath diameter is assessed after induction of anesthesia and at the end of surgery.
Nausea and vomiting	At 1 hour after surgery	Presence and severity of nausea and vomiting is assessed.

Trial Locations

Locations (1)

SMG-SNU Boramae Medical Center; 🇰🇷 Seoul, Korea, Republic of