To compare the effect of analgesia in two different types of additives to local anesthesia drugs in adductor canal block for lower limb surgeries.
Phase 2
- Conditions
- Health Condition 1: S829- Unspecified fracture of lower leg
- Registration Number
- CTRI/2023/02/049884
- Lead Sponsor
- Dr Sudeepthi K
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1)patients with American society of Anesthesiologists(ASA)physical status 1 and 2
2)patients aged between 18 and 60 years
3)patients with BMI more than 20 and less than 30kg/m2
4)informed valid consent of the patient
Exclusion Criteria
1)patients with history of hypersensitivity to local anesthetics
2)history of substance abuse
3)Preexisting neurological diseases like lower extremity neuropathy
4)pregnancy and lactation
5)local infection at the site of block
6)preexisting bleeding disorders and patients on anticoagulant therapy
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The duration of analgesia(time for rescue analgesia)Timepoint: requirement of rescue analgesia 3,6,12,18,24 hours after adductor canal block given
- Secondary Outcome Measures
Name Time Method Incidence of adverse event like bradycardia ,hypotensionTimepoint: assessment of heart rate and BP 3,6,12,18,24hrs after block given;Numerical rating scale(NRS) scores during rest and movementTimepoint: pain numerically assessed preoperatively and 3,6,12,18,24 hours after block is given postoperatively;Quadriceps motor strengthTimepoint: by straight leg raising test 0-5 scale measured preoperatively and 3,6,12,18,24 hours after block given;Ramsay sedation scoreTimepoint: assessment of sedation from level 1-6- 3,6,12.18,24hrs after block is given;Sensory analgesia by pinprick sensationTimepoint: pinprick sensation over saphenous nerve distribution in lower medial part of leg checked every 5 minutes till 30 minutes after block is given