Acute Postthoracotomy Pain - Impact of Gender

Completed

• Conditions: Gender; Postoperative Pain; Thoracotomy; Analgesia
• Interventions: Other: Thoracotomy

• Registration Number: NCT03281213
• Lead Sponsor: Medical University of Graz

Brief Summary

Adequate analgesia in thoracic surgery is essential to prevent severe postoperative complications, especially respiratory problems. Current knowledge about gender-related differences in pain states generally more frequent and intense pain and more demand for analgesics in women. Results about postsurgical pain in particular are very inconclusive.

The investigators tried to find out if gender has an influence on postthoracotomy pain and analgesics requirement.

Detailed Description

Not available

Study Timeline

• Study Start: 2010-07-01
• Primary Completion: 2014-12-31
• Study Completion: 2016-06-01
• Status Verified: 2017-09
• Study First Submitted: 2017-09-11
• Study First Submitted QC: 2017-09-12
• Last Update Submitted: 2017-09-12
• Study First Posted: 2017-09-13
• Last Update Posted: 2017-09-13

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 346

Inclusion Criteria

• open lung surgery between July 2010 and December 2014

Exclusion Criteria

• redo-thoracotomy
• chest wall or rib resection
• other approach than lateral thoracotomy
• additional incision at other site (e.g. laparotomy)
• chest trauma
• mesothelioma
• hemofiltration or haemodialysis
• longer than one day stay at intensive care unit
• pre-existent chronic pain and/or chronic opioid intake
• short stay in hospital

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Female	Thoracotomy	-
Male	Thoracotomy	-

Primary Outcome Measures

Name	Time	Method
Visual Analogue Scores	first 5 postoperative days
Analgesics requirement	first 5 postoperative days

Trial Locations

Locations (1)

Medical University of Graz, Division of Thoracic and Hyperbaric Surgery; 🇦🇹 Graz, Styria, Austria