Prevalence and Risk Factors for the Carriage of Bacteria and Clostridioid in Elderly Dependent Persons
- Conditions
- ElderlyHealthcare Associated Infection
- Interventions
- Other: Feces sampling at inclusion (J0)
- Registration Number
- NCT04579094
- Lead Sponsor
- Centre Hospitalier Universitaire de Nīmes
- Brief Summary
Brief summary : Very few studies have evaluated the prevalence of multi-drug resistant (MDR), highly resistant emerging bacteria and Clostridioides difficile toxinogenic (CDt) in residents and in healthcare workers (HCW) in nursing home (NH). Most of study were conducted in acute care services and were limited to specific bacterial species.
Hypothesis : The carriage of MDR bacteria in resident may be a risk factor for an outbreak in NH or in healthcare facility.
Primary outcome: The objective of this study is to estimate the prevalence for carriage of MDR bacteria and CDt in residents in NH.
Secondary outcomes:
* Estimate the prevalence for carriage of MDR bacteria and CDt toxigenic in HCW in NH.
* Identify the risk factors for carriage of MDR bacteria and CDt in residents in nursing home
* Identify the risk factors for carriage of MDR bacteria and CDt in healthcare workers in NH
* Evaluate the presence of cross-transmission of MDR bacteria and CDt in one or several NH
* Evaluate the association between the presence of cross-transmission of MDR bacteria and CDt in a NH and the management of infection control
* Establishment a collection of stool samples
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 1000
Not provided
Not provided
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description 2/healthcare workers (HCW) Feces sampling at inclusion (J0) - 1/elderly dependent persons Feces sampling at inclusion (J0) -
- Primary Outcome Measures
Name Time Method Presence or absence of multi-drug resistant bacteria in residents' feces. at inclusion (J0) prevalence of carriage of multi-drug resistant bacteria
Presence or absence of Highly Resistant and Emerging Bacteria in residents' feces. at inclusion (J0) prevalence of carriage of Highly Resistant and Emerging Bacteria
Presence or absence of Clostridioids difficult toxinogenic in residents' feces. at inclusion (J0) prevalence of carriage of Clostridioids difficult toxinogenic
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
CHU de Nîmes, Hôpital Universitaire Carémeau
🇫🇷Nîmes, France