Determination of the Impact of Different Cereals on Mineral Status
- Conditions
- normal mineral bioavailabilityDiet and Nutrition - Other diet and nutrition disorders
- Registration Number
- ACTRN12611001105932
- Lead Sponsor
- CSIRO Food Futures National Research Flagship
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Female
- Target Recruitment
- 80
female, aged <75 years, postmenopausal >6years and not undergoing hormone replacement therapy.
Not on vitamin or mineral supplements or unwilling to abstain for the duration of the study.
Not received any medication that in the opinion of the investigator could interfere with the study and no medications likely to modulate gut and/or metabolic function.
Bone mineral density in the osteoporotic density range.
Intolerance to lactose.
Use of any form of drug therapy or medication or supplements that may interfere with bowel or bone function (such as antibiotics, laxatives, osteoporotic treatments etc).
Known or suspected personal history or family history of adverse events, hypersensitivity or intolerance to consumption plant-based foods which will be tested in this study.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method calcium absorption - dual stable isotope laboratory analysis[week 8]
- Secondary Outcome Measures
Name Time Method mineral balance - urine laboratory analysis[baseline, week 2, 4, 6, 8];DXA scan for bone mineral density[baseline];calcium and bone biomarkers - laboratory blood analysis[baseline, week 2, 4, 6, 8]