Effect of N-ACETYLCYSTEINE In Treatment of Antitubercular drug induced liver injury.
Phase 3
- Conditions
- Health Condition 1: A15-A19- Tuberculosis
- Registration Number
- CTRI/2024/01/061627
- Lead Sponsor
- AIIMS jodhpur
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patient diagnosed with antitubercular drug induced hepatotoxicity.
Patients Age >18 year of either sex and meet the all / any of the following criteria:
(i) a rise of five times the upper limit of normal levels of serum AST and/or ALT
without symptom of hepatotoxicity.
(ii) a rise of two times the upper limit of normal level of serum bilirubin.
(iii) More than 3 times increase in AST and/or ALT levels together with the hepatitis
symptoms
Exclusion Criteria
1.History of alcoholism and known case of alcoholic liver disease.
2. Known case of HIV, HBV, HCV.
3. Liver injury due to drugs other than ATT.
4. Pregnant or breastfeeding women.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method