The effectiveness of High-Intensity Laser Therapy (at 1580 Joules) in de Quervains tenosynovitis: A randomized double-blinded controlled trial

Phase 2

• Conditions: Visual analogue scale and lateral pinch strength of patient diagnosed with de Quervain' s tenosynovitis before and after treatments of high intensity laser therapy (1580Joules) compared to control group.Wrist/hand function before and after treatments.Adverse event of high intensity laser therapy; de Quervain' s tenosynovitis; High-Intensity Laser Therapy (HILT); Visual Analogue scale (VAS); Patient-Rated Wrist Evaluation (PRWE)

• Registration Number: TCTR20210712004
• Lead Sponsor: /A

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2021-07-12
• Study Completion: 2022-09-30
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Pending (Not yet recruiting)
• Sex: All
• Target Recruitment: 36

Inclusion Criteria

1.Diagnosis of de Quervain's tenosynovitis
-The 1st dorsal compartment pain and tenderness
-Symptom provoked by thumb extension and abduction
-Finkelstein's test: positive
2.Unilateral affected wrist and developed more than 1 month
3.Moderate to severe pain (VAS 40-80/100 mm)
4.Informed consent
5.Free from any NSAID medication for 2 weeks

Exclusion Criteria

1. History of others wist and distal forearm disorders
2. Skin problems at the affected wrist
3. History of surgery or trauma or deformity of the affected limb
4. Neurological disease(e.g.cervical spondylosis with radiculopathy)
5. Systemic infection or rheumatologic disease
6. Contraindication of HILT(e.g. pregnancy, tumor, uncontrolled Diabetes Mellitus etc.)
7. Allergic to acetaminophen
8. On medication that has drug interaction with acetaminophen
9. History of local steroid injection at affected area in 3 months
10. Cannot wear splint due to allergic to splint or other reasons

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pain score pre-treatment, within 48 hours post-last-treatment and 3 weeks post-last-treatment Visual analogue scale(VAS),Lateral pinch strength pre-treatment, within 48 hours post-last-treatment and 3 weeks post-last-treatment Jamar pinch gauge(Kg.)

Secondary Outcome Measures

Name	Time	Method
Functional outcome pre-treatment, within 48 hours post-last-treatment and 3 weeks post-last-treatment Patient-rated wrist/hand evaluation-Thai (PRW/HE -Thai),Adverse Event during entire study Medical record document