Proteomic Analysis on Myopic Children Using Orthokeratology Lenses With Good or Poor Myopic Control. The ProMOC Study
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Difference in protein levels measured by mass spectrometry label-free quantification (LFQ) between children using orthokeratology lenses with different levels of myopia control effectiveness
研究概览
简要总结
The key objective of the study is to gain an understanding of the biochemical processes that contribute to orthokeratology lenses being more effective in specific individuals compared to others. With this knowledge, we hope to optimize treatment effectiveness in those currently experiencing less favorable outcomes from treatment in the future.
The primary aim is to investigate differences in protein levels in children using orthokeratology lenses with various effects of myopia control.
Hypothesis: There is a significant difference in the expression of molecules in children with various effects of myopia control.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 5 Years 至 14 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Children treated with orthokeratology lenses.
- •Children on or above the 95th percentile of myopia growth curves for European children at the time of treatment initiation.
- •Treatment and follow-up duration ≥ 6 months.
排除标准
- •Current use of eye drops.
- •Objective signs of dry eyes on slit-lamp examination.
- •Active eye infection.
结局指标
主要结局
Difference in protein levels measured by mass spectrometry label-free quantification (LFQ) between children using orthokeratology lenses with different levels of myopia control effectiveness
时间窗: At baseline
次要结局
未报告次要终点