Proteomic Analysis on Myopic Children Using Orthokeratology Lenses With Good or Poor Myopic Control
Recruiting
- Conditions
- MyopiaHealthyOrthokeratology
- Registration Number
- NCT06647472
- Lead Sponsor
- Vejle Hospital
- Brief Summary
The key objective of the study is to gain an understanding of the biochemical processes that contribute to orthokeratology lenses being more effective in specific individuals compared to others. With this knowledge, we hope to optimize treatment effectiveness in those currently experiencing less favorable outcomes from treatment in the future.
The primary aim is to investigate differences in protein levels in children using orthokeratology lenses with various effects of myopia control.
Hypothesis: There is a significant difference in the expression of molecules in children with various effects of myopia control.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 25
Inclusion Criteria
- Children treated with orthokeratology lenses.
- Children on or above the 95th percentile of myopia growth curves for European children at the time of treatment initiation.
- Treatment and follow-up duration ≥ 6 months.
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Exclusion Criteria
- Current use of eye drops.
- Objective signs of dry eyes on slit-lamp examination.
- Active eye infection.
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Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Difference in protein levels measured by mass spectrometry label-free quantification (LFQ) between children using orthokeratology lenses with different levels of myopia control effectiveness At baseline
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Øjenafdelingen, Vejle Sygehus
🇩🇰Vejle, Denmark