Endoscopic Tri-Modal Imaging (ETMI) for the detection of early neoplasia in patients with Barrett*s esophagus (BE) in tertiary referral centers; a randomized cross-over multi-center study.
Completed
- Conditions
- Barrett's esophagusesophageal cancer10017990
- Registration Number
- NL-OMON30430
- Lead Sponsor
- Academisch Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 31
Inclusion Criteria
Age >18 years
Prior diagnosis of Barrett's esophagus
Minimum Barrett's length of C>2M>2 or C<2M>4 according to the Prague C&M classification
Written informed consent
Exclusion Criteria
Presence of esophagitis > grade A according to the LA classification of erosive esophagitis
Presence of conditions precluding histological sampling of the esophagus
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Number of patients detected with dysplasia.<br /><br>Number of lesions detected with dysplasia.</p><br>
- Secondary Outcome Measures
Name Time Method <p>Positive predictive value of high-resolution white light endoscopy and<br /><br>autofluorescence imaging.<br /><br>Reduction of fals-positive findingfs with narrow band imaging.</p><br>