ocoregional control of completion parotidectomy and radiotherapy compared with radiotherapy in patients with high-grade parotid cancer confining in the superficial lobe who had received superficial or conservative parotidectomy
Phase 2
Recruiting
- Conditions
- This study will be conducted in patient diagnosed as high-grade parotid cancer confining in the superficial lobe of parotid glandDeep lobe parotidectomy, Completion parotidectomy, Total parotidectomy, Superficial parotidectomy, High-grade parotid cancer
- Registration Number
- TCTR20230202003
- Lead Sponsor
- Faculty of Medicine, Chulalongkorn University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
The patient was diagnosed with parotid cancer and received conservative parotidectomy or superficial parotidectomy and has all the inclusion criteria.
1.Tumor confining only in the superficial lobe of the parotid gland confirmed by pre-operative CT scan
2.Final histopathological report was high-grade parotid cancer
Exclusion Criteria
1.Age <18 years
2.Pregnancy
3.Pre-operative ipsilateral facial nerve palsy
4.R2 resection (gross residual tumor at parotid bed after primary surgery)
5.Tumor extends to deep parotid lobe either tumor extension or deep parotid lymph node involvement
6.Non-parotid primary cancer
7.History of prior radiation in head and neck
8.Receiving concurrent chemotherapy after surgery
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method locoregional recurrence 12 month after complete treatment Local and regional recurrence at 1 year
- Secondary Outcome Measures
Name Time Method Complication of completion surgery 0,3,6 month after complete treatment Facial nerve paresis