Regulatory T-cell function in psoriasis vulgaris - Regulatory T cells in psoriasis

niversitätsklinikum Gießen und Marburg, Standort Marburg0 个研究点目标入组 48 人开始时间: 2011年2月9日最近更新: 2024年8月19日

适应症

试验速览

暂无简介。

•who are aged 18 years up to 65 years
•clinical diagnosis of psoriasis for >6 month
•who have plaque-type psoriasis (PASI>10)
•psoriasis affected body surface >10%
•who have been informed of the study procedures and medication and have provided written informed consent

•patients with contraindications for treatment with TNF-alpha inhibitors and fumaric acid esters;
•women who are pregnant or who are breast-feeding. Women of child-bearing potential must follow a medically recognized form of contraception
•who are currently receiving or have received systemic therapy for psoriasis within four weeks prior to the first administration of study medication.
•who are currently receiving or have received monoclonal antibody therapy for psoriasis within four weeks to the first administration of study medication.
•who are currently receiving or have received phototherapy within four weeks prior to the first administration of study medication.
•tuberculosis anamnesis, infections (Hepatitis B, C, HIV)
•with a history of lymphoproliferative disorders, malignancies, demyelinating disease, severe heart failure
•who have a history of substance abuse (drugs or alcohol) or any factor (e.g. serious psychiatric condition) which limits the patient’s ability to cooperate with the study procedures
•who are uncooperative, known to miss appointments (according to patient’s records) and are unlikely to follow medical instructions or are not willing to attend regular visits

发起方

niversitätsklinikum Gießen und Marburg, Standort Marburg