ISRCTN50142780已完成未知
Can changes in central venous oxygen saturation and central venous - arterial partial pressure of carbon dioxide difference predict changes in stroke volume in high risk surgical patients?
James Cook University Hospital (UK)0 个研究点目标入组 25 人开始时间: 2012年1月24日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 25
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 性别
- All
入选标准
- •1. Elective major open abdominal surgery (gastrointestinal, urological, gynaecological or vascular procedures with an expected duration of at least 90 minutes)
- •2. Requirement for invasive haemodynamic monitoring including arterial and central venous blood pressure and CO measurement
- •3. More than 50 years of age and at least one of the following:
- •3.1. Renal impairment (serum creatinine > 130 µmol/l)
- •3.2. Diabetes mellitus
- •3.3. Aged 65 years and over
- •3.4. Presence of a risk factor for cardiac or respiratory disease:
- •3.4.1. Exercise tolerance = 6 metabolic equivalents (MET?s)
- •3.4.2. Anaerobic threshold = 14 ml/kg/min
- •3.4.3. Past medical history of ischaemic heart disease
- •3.4.4. Heart failure
- •3.4.5. Moderate or severe valvular disease
- •3.4.6. Chronic obstructive pulmonary disease (COPD)
- •3.4.7. Radiographically confirmed chronic lung disease (COPD, fibrosis)
排除标准
- •1. No consent
- •2. Pregnancy
- •3. Emergency surgery
- •4. Vascular surgery involving aortic cross clamping
- •5. Allergy to Gelofusin® and Volulyte®
- •6. Laparoscopic surgery
研究者
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