Effect of High-intensity Interval Training Combined With DASH Diet on Arterial Stiffness in Hypertensive Patients

Not Applicable

Recruiting

• Conditions: Hypertension; Arterial Stiffness

• Registration Number: NCT07188272
• Lead Sponsor: Deraya University

Brief Summary

Cardiovascular disease (CVD) is one of the leading causes of mortality worldwide and a major risk factor for morbidity worldwide . It is necessary to reduce the incidence and risk factors of CVD, as physical activity is known to reduce mortality from CVD. Arterial stiffness and hypertension are closely related in pathophysiology. Chronic high blood pressure (BP) can lead to arterial wall damage by mechanical stress, endothelial dysfunction, increased inflammation, oxidative stress, and renin-angiotensin-aldosterone system (RAAS) activation. HIIT has been shown to be equally or even better at stimulating health benefits than moderate-intensity continuous training (MICT) and is considered a time-saving aerobic exercise for reducing arterial stiffness in HTN patients

Detailed Description

Not available

Study Timeline

• Study Start: 2025-07-10
• Status Verified: 2025-09
• Study First Submitted: 2025-09-15
• Study First Submitted QC: 2025-09-20
• Last Update Submitted: 2025-09-20
• Study First Posted: 2025-09-23
• Last Update Posted: 2025-09-23
• Primary Completion: 2025-12-10
• Study Completion: 2026-01-01

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• Their age< 35 up to 50 years old
• Both sexes.
• Controlled HTN ( stage 1,B.P 140-159 mmhg / 90-99 mmhg and stage 2, B.P 160-179 mmhg-100-109 mmhg )
• Hemodynamic stable. Able to provide informed consent

Exclusion Criteria

• Uncontrolled hypertension.
• Severe HTN <180/110 mmhg
• Renal dysfunction
• Unstable cardiac conditions
• Severe pulmonary disease that limit exercise
• Impaired cognition
• Musculoskeletal problems that made it difficult to do exercise

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Pulse Wave Velocity	each week	normal level 60-100 per minutes

Trial Locations

Locations (1)

Waleed Mohamed Abdelmohsen Abdelsalalm; 🇪🇬 Minya, Egypt