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Clinical Trials/NCT05638516
NCT05638516
Completed
N/A

Improving Mental Health in Youth and Lowering Risk for Obesity Through a Digital Preventative Product

Ksana Health1 site in 1 country73 target enrollmentNovember 7, 2022

Overview

Phase
N/A
Intervention
Not specified
Conditions
Mental Health Disorder
Sponsor
Ksana Health
Enrollment
73
Locations
1
Primary Endpoint
Change in depressive symptoms
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

The goal of this study is to test the feasibility and utilization of a redesigned mobile app and health coaching platform (Vira) in youth (aged 18-25 years) with elevated depressive symptoms who are overweight/obese and/or self-report parental history of overweight/obesity.

Eligible participants will be randomly assigned to one of two groups: one group will use the Vira mobile app intervention with support from a health coach, and the other group will use the Vira mobile app intervention without coaching. Both groups will use the app for 12 weeks.

Detailed Description

The primary aim of this project is to examine the feasibility and utilization of a redesigned mobile app and health coaching platform (Vira) in a 2 x 2 (gender x condition) designed pilot study in a sample of 100 youth (18-25 years old) with (1) elevated depressive symptoms (PHQ-8 score ≥10) and (2) overweight/obesity (BMI ≥ 25 and/or reporting a parental history of overweight/obesity). The study will examine the feasibility and utilization of the mobile app intervention with coaching compared to that of the mobile app intervention without coaching. This is an exploratory pilot study; therefore, no formal sample size calculation was conducted. It is anticipated that 1,000 individuals will be screened, of which 20% will be eligible, and that 50% of those eligible will agree to participate (final N = 100, 50 per arm).

Registry
clinicaltrials.gov
Start Date
November 7, 2022
End Date
May 6, 2023
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Ksana Health
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Age 18-25
  • Live in the United States
  • English fluency and literacy
  • Have access to an Android or iOS device
  • Elevated depressive symptoms (PHQ-8 score of 10 or above)
  • Overweight (BMI of 25 or above) OR reporting a parental history of overweight or obesity

Exclusion Criteria

  • Previous participation in this study
  • Major mental or physical illness that will interfere with completing intervention and/or assessment activities.

Outcomes

Primary Outcomes

Change in depressive symptoms

Time Frame: 12 weeks

Pre- to post-intervention changes in depressive symptoms will be assessed by the Patient Health Questionnaire (PHQ-8) an 8-item participant-report measure for screening for depression and for establishing depression severity. The total score ranges from 0-24, with a higher score indicating greater depression symptom severity.

Number of active days in the Vira mobile app intervention and health coaching platform

Time Frame: 12 weeks

To measure feasibility of implementation, the total number of active days using Vira during the study will be objectively collected via the Vira platform.

Number of features used

Time Frame: 12 weeks

To measure feasibility of implementation, the total number of features used during the study will be objectively collected via the Vira platform.

Acceptability of the mobile app intervention

Time Frame: 12 weeks

Acceptability of the mobile app intervention and health coaching platform will be assessed using 11 items adapted from the Technology Acceptance Model. Scores range from 11 to 77, with higher scores indicating greater acceptability.

Study Sites (1)

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