Impact of acute and chronic regular exercise on arterial stiffness and reflection measures in coronary artery disease patients
- Conditions
- Health Condition 1: I700- Atherosclerosis of aorta
- Registration Number
- CTRI/2021/10/037127
- Lead Sponsor
- Jayoti Vidyapeeth Womens University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
the presence of CAD, which is defined as the patient having at least one of the following: angiographically documented stenosis >=50% in at least one major coronary artery; prior history of myocardial infarction (MI), percutaneous coronary intervention (PCI), or coronary artery bypass graft (CAGB) surgery; positive exercise stress test determined by a positive nuclear scan, or symptoms of chest discomfort accompanied by electrocardiographic (ECG) changes of > 1mm horizontal or down sloping ST segment depression.
non-cardiac surgical procedure within two months, MI or CABG within two months, PCI within one month, NYHA class II-IV symptoms of heart failure, documented valve stenosis, documented severe chronic obstructive pulmonary disease, symptomatic peripheral arterial disease, unstable angina, uncontrolled hypertension, uncontrolled atrial arrhythmia or ventricular dysrhythmia, insulin requiring diabetes mellitus, and any musculoskeletal abnormality that would limit exercise participation.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary objective of this research is to identify whether long term exercise can beneficially modify hemodynamic profile especially pulse wave velocity and augmentation index in subjects with Coronary artery diseaseTimepoint: 4 weeks and 8 weeks
- Secondary Outcome Measures
Name Time Method This study will further investigate the mechanisms for changes in hemodynamic profile benefits to improve CVD risk for patients with CADTimepoint: 4 weeks and 8 weeks