Effect of N-Acetylcysteine on Autologous Fat Graft Survival

Phase 4

Withdrawn

• Conditions: Adipose Tissue Atrophy; Deformity of Reconstructed Breast; Graft Loss

• Registration Number: NCT02788292
• Lead Sponsor: Nova Scotia Health Authority

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2016-4-18
• Last Update Posted: 2 September 2024

Recruitment & Eligibility

• Status: Withdrawn
• Sex: Female
• Target Recruitment: Not specified

Inclusion Criteria

Inclusion Criteria:<br><br> 1. Women<br><br> 2. Desire and surgical indication for liposuction of the thigh/hip region for women<br> already undergoing elective breast reduction surgery<br><br> 3. Age 18-45 years<br><br> 4. BMI of 20-30<br><br> 5. ASA Class I<br><br>Exclusion Criteria:<br><br> 1. Known chronic illnesses: Diabetes, HIV, renal/liver failure, metabolic disease,<br> history of cancer or family pre-disposition of cancer, peripheral vascular disease,<br> illness that would preclude a general anaesthetic<br><br> 2. Pregnancy or planned pregnancy within 1 year<br><br> 3. Contraindications to CT<br><br> 4. Previous hip/thigh surgery or injury<br><br> 5. Previous lower leg surgery/injury<br><br> 6. Smoker<br><br> 7. Breastfeeding<br><br> 8. Other disease according to investigator's judgment

Exclusion Criteria

Not provided

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change in fat graft volume over time

Secondary Outcome Measures

Name	Time	Method
Weight of fat graft;Fat graft vascularity;Fat graft quality;Adverse effects or complications