Combined Compared to Sequential Cognitive and Physical Training in Anterior Cruciate Ligament Reconstructed Individuals

Not Applicable

Recruiting

• Conditions: Anterior Cruciate Ligament Reconstruction Rehabilitation

• Registration Number: NCT06845150
• Lead Sponsor: Michelle C. Haas

Brief Summary

The goal of this clinical trial is to investigate changes in cognitive and physical performance after 10 weeks of dual or single task training in anterior cruciate ligament (ACL) reconstructed individuals. The main questions it aims to answer are:

* Does cognitive performance in ACL reconstructed individuals change after multiple training sessions incorporating single versus dual-task?

* Does physical performance and intrinsic motivation for training change over the course of 10 weeks when performing single versus dual-task training sessions?

* What movement patterns do ACL reconstructed individuals show during a dual-task training in an immersive environment?

Researchers will compare a combined dual-task training (combined physical and cognitive training) to a single task training (physical and cognitive training separately) to see if there are changes on cognitive performance depending on the training type.

Participants will:

* Perform dual-task or single task training twice per week for 10 weeks

* Visit the clinic before and after the training period for tests

* Visit the movement laboratory once for analysis of movement patterns

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2025-02-13
• Study First Submitted QC: 2025-02-19
• Study First Posted: 2025-02-25
• Status Verified: 2025-06
• Study Start: 2025-06-05
• Last Update Submitted: 2025-06-12
• Last Update Posted: 2025-06-13
• Primary Completion: 2026-06
• Study Completion: 2026-06

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 32

Inclusion Criteria

• 18-40 years old
• At least 6 months after ACL injury
• Surgically reconstructed ACL
• At least 2 hours of sports participation before the injury
• Written consent of the attending surgeon to perform intensified training methods including one-legged jumps at 6 months after surgery after the first visit
• Ability to give informed consent as documented by signature
• Ability to understand instructions in German or English
• BMI < 28 kg/m^2
• Availability to take part in at least 70% of all training sessions

Exclusion Criteria

• Surgery on the contralateral leg during the last 12 months
• Acute or chronic musculoskeletal, neurological, or cardiopulmonary disorders
• Unadjusted vision problems
• Concussion during the last 6 months
• Pregnancy
• Breastfeeding
• Amputation
• Inflammatory pain or swelling during exercising

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Interference	Baseline, after 5 weeks of training, after 10 weeks of training	Measured by the difference in reaction time of congruent and incongruent stimuli of the Flanker task.
Response inhibition	Baseline, after 5 weeks of training, after 10 weeks of training	Measured by the accuracy of Go/No-Go-stimuli

Secondary Outcome Measures

Name	Time	Method
Intrinsic motivation	At the end of each training session (2x/week for 10 weeks)	German version of the short scale for intrinsic motivation (Kurzskala Intrinsische Motivation). For each of the 12 items there is a 5-point Likert-Scale resulting in values of 0-4. Therefore, the total score ranges from 0 to 48. The higher the score, the higher the intrinsic motivation.
Kinematics and kinetics of the lower extremities	Baseline and after 10 weeks of training	Ground reaction forces, angles and moments of hip, knee, and ankle during functional tasks
Jumping performance - contact time	Baseline and after 10 weeks of training	Contact time during jumping on force plates.
Jumping performance - peak force	Baseline and after 10 weeks of training	Peak force during jumping on force plates.
Strength	Baseline and after 10 weeks of training	Peak force of hamstring, quadriceps, hip abduction, and hip adduction

Trial Locations

Locations (2)

KSW Kantonsspital Winterthur; 🇨🇭 Winterthur, Switzerland

ZHAW Zurich University of Applied Sciences; 🇨🇭 Winterthur, Switzerland