跳至主要内容
临床试验/NCT02635308
NCT02635308已完成不适用

Enhanced Rehabilitation Targeting Strength and Movement Pattern Symmetry Following Hip Fracture

University of Utah0 个研究点目标入组 24 人开始时间: 2013年4月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
24
主要终点
muscle strength

研究概览

简要总结

This study evaluates the feasibility of implementing a unilaterally biased high-intensity resistance training to facilitate restorative vs. compensatory recovery after "usual care" physical therapy among older adults who have recently incurred a hip fracture. Additionally, physical performance during a sit-to-stand task, muscle function (strength/power), physical function measures, muscle composition, and muscle quality (force/unit area), are assessed before and after targeted high-intensity resistance training.

详细描述

Hip fracture is a major public health concern in the United States. Fall-related injuries constitute the leading cause of deaths and disabilities among persons over age 65 years. Hip fracture is consistently identified as one of the most frequent, costly, and devastating non-lethal injuries from a fall. Rehabilitation after hip fracture remains largely unchanged over the last 30 years despite evidence that high-intensity rehabilitation can benefit physical function after hip fracture beyond the recovery typical with "usual care".

Asymmetries demonstrated in physical performance of various tasks, such as gait, balance, and a sit-to-stand transfer, and impaired surgical limb muscle function are evident for years after hip fracture, and may contribute to the high rate of falls and declining function typically encountered by older adults recovering from hip fracture. Implementing a high-intensity rehabilitation approach targeting asymmetries after hip fracture is likely to yield improved symmetry in both physical function and muscle function. This study will recruit older adults who have recently incurred a hip fracture and completed "usual care" physical therapy to determine whether a high-intensity rehabilitation strategy targeting asymmetries in movement strategies and muscle function of the surgical limb can be successfully implemented in this challenging population. In particular, recruitment, adherence to rehab protocol parameters, and retention will be addressed among those who initiate high-resistance training at approximately 8-12wk after hip fracture incidence.

In addition, the investigators will explore the potential of targeted unilaterally-biased resistance training to improve surgical limb function and performance after hip fracture. Specifically, physical performance, muscle function, and muscle quality/composition are recorded and compared pre-/post-training to determine whether improvements occur in conjunction with high-intensity rehabilitation training. Additionally, the investigators will measure improvements in muscle composition that occur as a result of this high-intensity resistance training.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Treatment
盲法
None

入排标准

年龄范围
50 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Age greater than 50 yrs
  • Ability to sign informed consent
  • Mental Status MoCA score greater than 22
  • Independent community ambulatory prior to hip fracture
  • Ability to ambulate greater than 50 feet with or without assistive device

排除标准

  • Previous hip fracture
  • Bilateral hip fracture
  • Pathological fracture
  • Expected life Expectancy less than one year
  • Permanently institutionalized
  • Fracture result of multi-trauma
  • Cardiac abnormalities
  • Neuromuscular impairments
  • Unstable medical conditions
  • Elevated systolic greater than 150 or diastolic blood pressure greater than 100
  • Implanted electronic devices
  • History of stroke with motor disability
  • Alcohol or drug abuse
  • Respiratory disease
  • Conditions deemed exclusionary by PI or physician

结局指标

主要结局

muscle strength

时间窗: 12 week

Knee extension muscle strength was measured on an isokinetic dynamometer as a maximum voluntary isometric contraction in newtons (N) of force. The average of three trials was used.

muscle power

时间窗: 12 week

Leg extension muscle power was measured on a Nottingham power rig in watts (W). The average of three trials was used.

次要结局

  • Timed up and Go Test(12 week)
  • Lower Extremity Measure(12 week)
  • muscle mass(12 week)
  • Berg Balance Scale(12 week)
  • Stair Climb Test(12 week)
  • sit-to-stand task performance(12 week)
  • usual gait speed(12 week)
  • Activities Specific Balance Scale(12 week)
  • Six minute walk test(12 week.)
  • Modified Physical Performance Test(12 week)
  • Stair Descent Test(12 week)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Robin Marcus

Ph.D.

University of Utah

相似试验