Magneto-encephalography (MEG) to image the brain*s role in the analgesic effects of Spinal Cord Stimulation (SCS), an explorative study
- Conditions
- cortical correlates of neuropathic painworkingsmechanisms of spinal cord stimulation10034606
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 25
a patient with SCS must meet the following criteria:
* Over 18 years,
* SCS for at least 3 months,
* Stable response to conventional (tonic) stimulation,
* Pulse generator suitable for burst stimulation,
* Active tip of the implanted electrode at spinal level Th8 or below,
* Pulse generator implanted in the lower body,
* Capable of participation: travelling to the institute and filling in the questionnaires;a control subject with pain must meet the following criteria:
* Over 18 years,
* Chronic neuropathic pain in the lower body part,
* Preferably on a waiting list for a SCS implant,
* Capable of participation: travelling to the institute and filling in the questionnaires.;a control subject without pain must meet the following criteria:
* Over 18 years,
* No pain or other neurological disease,
* Capable of participation: travelling to the institute and filling in the questionnaires.
* Severe pain that is interfering with the pain that the SCS is used for,
* Hospitalised or another form of serious decline of general health.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Differences in the power in frequency bands in cortical pain processing areas<br /><br>as well as attention areas under the three stimulation settings. Differences in<br /><br>coherence and frequency coupling within pain processing areas, and between pain<br /><br>processing areas and attention areas. Modulation of evoked responses to<br /><br>peripherally applied electrical stimulation. </p><br>
- Secondary Outcome Measures
Name Time Method <p> .</p><br>