A study to compare the Efficacy of IV Esmolol VS IV Dexmedetomidine in blocking pressor response to Laryngoscopy andIntubation in Patients undergoing Elective Major Surgeries.
- Conditions
- Health Condition 1: O- Medical and SurgicalHealth Condition 2: O- Medical and Surgical
- Registration Number
- CTRI/2021/06/034181
- Lead Sponsor
- Dr Arundhati Chadha
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 56
Patients undergoing Elective Major surgeries,
Patient related factors,
1. Adults between 30 to 65 yrs.
2. BMI between 18.5 to 30 kg per m2 .
3. Mallampati Airway class I and II.
4. ASA I, II and III patients.
Surgery related factors,
1. Operative time more than 4 hours.
2. Expected Excessive intra operative blood loss.
3. Expected peri operative blood transfusion of more than or equal to 2 PRBC.
4. And, or one of the following surgeries,
i. Radical hysterectomy.
ii. TURP.
iii. Discectomy, Laminectomy.
iv. Thyroidectomy.
v. lung operations.
vi. Ileostomy, colectomy.
vii. Neck lymph node dissection.
viii. Neurosurgeries.
ix. Heart surgeries.
1. Unwillingness to give consent.
2. Allergy to any of the drugs.
3. Anticipated Difficult Airway.
4. Intubation attempts lasting for more than 30 secs.
5. Left ventricular ejection fraction less than 45 percent.
6. Pregnant and lactating females.
7. Acute or Chronic Renal Disease.
8. Acute or Chronic Liver Disease.
9. Chronic Obstructive Pulmonary Disease.
10. ASA IV, V and VI patients.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method