Comparison between two drugs intravenous dexmedetomidine and esmolol for attenuation of sympathetic response during endotracheal extubation.
Phase 2
- Conditions
- Health Condition 1: K810- Acute cholecystitisHealth Condition 2: O- Medical and Surgical
- Registration Number
- CTRI/2022/05/042940
- Lead Sponsor
- Dr Rashmi Naik Bhuaarya
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
ASA Physical Status ââ?¬â?? I & II
BMI (18.5-24.9)
Patient undergoing elective surgery under general anaesthesia and endotracheal intubation
Exclusion Criteria
Patientââ?¬•s refusal
Patient with known allergy to dexmedetomidine and esmolol
Surgery lasting for more than two hour
Patient with h/o hypertension, ischaemic heart disease, aortic stenosis, left ventricular failure, atrio-ventricular conduction block sinus bradycardia, asthma, chronic obstructive pulmonary disease
Severe hepatic and renal disease
Patient receiving antihypertensives, MAO inhibitors
Pregnant and lactating woman
Cases encountered with difficult intubation
Anticipated difficult airway
Novel corona virus positive
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method