Esmolol versus Dexmedetomidine for Deliberate Hypotension during Functional Endoscopic Sinus Surgery

Not Applicable

• Conditions: Surgery; Deliberate Hypotension during Functional Endoscopic Sinus Surgery

• Registration Number: PACTR201801002878287
• Lead Sponsor: Faculty of Medicine, Menoufia University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2017-12-15
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 36

Inclusion Criteria

¿Adult patients, 20 to 45-year-old, of both genders, scheduled for elective FESS surgery.
¿American society of anesthesiologists class (ASA) I and II patients.

Exclusion Criteria

¿Patient refusal.
¿ASA class III and IV.
¿Any known hypersensitivity or contraindication to esmolol or dexmedetomidine.
¿Patients with bleeding diathesis, respiratory problems, liver failure, kidney insufficiency or heart diseases (heart block, or myocardial ischemia).
¿Patient with poorly controlled arterial hypertension (blood pressure higher than 140/90 mmHg).
¿Patients planned for redo surgery for recurrent rhinosinusitis.
¿Patients on anticoagulant, ¿2 agonist or ¿ blocker therapy.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
¿Total blood loss (ml) during the operation, which is collected by suction added to the estimated from nasal packing.

Secondary Outcome Measures

Name	Time	Method
¿Surgeon's satisfaction score with 4 points subjective scale (18) at the end of surgery, as follows:-. ¿1 = Bad. ¿2 = Moderate. ¿3 = Good. ¿4 = Excellent.