Does Fluid Requirement Decrease With the Use of Pneumatic Compression Device on Lower Limbs
- Conditions
- Fluid Overload
- Interventions
- Device: HUNTLEIGH FLOWTRON ACS900
- Registration Number
- NCT03789474
- Brief Summary
Impact of intraoperative use of pneumatic peristaltic compression device on hemodynamics vis a vis on fluid requirement during general anaesthesia and surgery.
- Detailed Description
Induction of general anaesthesia is associated with cardiac depression and peripheral vasodilatation resulting in hypotension .This hypotension can be corrected by giving intravenous fluid, or the vasoconstrictor. While optimum fluid balances in the perioperative period is of vital importance in overnight fasting patients to correct the fluid deficit, any fluid overload is not only counterproductive to the heart function but is associated with fluid retention in body and edema in postoperative period.
Peristaltic pneumatic compression device, a variant of intermittent sequential compression of legs, uses higher pressure and longer compression cycles to avoid venous stasis in immobilized patients. Sequential compression devices have sleeves with pockets of inflation, which works to squeeze on the appendage in a milking action .The most distal areas will inflate initially, and the subsequent pockets will follow in the same manner. The primary aim of the device is to squeeze blood from the underlying deep veins to proximal side. When the inflatable sleeves deflate, the veins will replenish with blood. The intermittent compressions of the sleeves will ensure the movement of venous blood . Peristaltic Pneumatic Compression of the legs significantly reduces fluid demand and enhances stability during minor ear, nose, and throat surgery. Peristaltic Pneumatic Compression has the potential to support fluid restriction regimens during surgery .
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 60
- ASA(American Society of Anaesthesiologists) grade I or II, of both genders
- Age group of 25 to 50 years
- Patients undergoing surgeries under GA(General Anaesthesia) for 2-3 hours
- Patients expected to get major blood loss
- Burns patients.
- Patients with significant cardiac diseases.
- Patients with pulmonary diseases and impaired renal function.
- Lower limb surgeries and abdominal surgeries
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Group B HUNTLEIGH FLOWTRON ACS900 Intervention:peristaltic pneumatic compression device was placed on the legs of the patient and was active. HUNTLEIGH FLOWTRON ACS900 calf length device was used.
- Primary Outcome Measures
Name Time Method Mean Blood Pressure at T4 60 minutes after induction Mean blood pressure measurement at T4
Diastolic Blood Pressure at T1 immediately after induction Diastolic blood pressure measurement at T1
Diastolic Blood Pressure at T3 30 minutes after induction Diastolic blood pressure measurement at T3
Mean Blood Pressure at T0 15 minutes pre induction Mean blood pressure measurement at T0
Mean Blood Pressure at T1 immediately after induction Mean blood pressure measurement at T1
Heart Rate at T0 15 minutes pre induction heart rate monitoring at T0
Heart Rate at T1 post induction heart rate heart rate monitoring at T1
Heart Rate at T4 60 minutes after induction heart rate monitoring at T4
Systolic Blood Pressure at T4 60 min after induction systolic blood pressure measurement at T4
Diastolic Blood Pressure at T2 15 minutes after induction Diastolic blood pressure measurement at T2
Heart Rate at T2 15 minutes after induction heart rate monitoring at T2
Systolic Blood Pressure at T1 post induction systolic blood pressure measurement at T1
Mean Blood Pressure at T2 15 minutes after induction Mean blood pressure measurement at T2
Femoral Vein Velocity at T0 15 minutes pre induction Femoral vein velocity measuement at T0
Femoral Vein Velocity at T6 after 30 minutes in post anaesthesia care unit Femoral vein velocity measurement at T6
Inferior Venacava Diameter (Minimum) at T0 15 min pre induction inferior venacava diameter (minimum) meaurement at T0
Inferior Venacava Diameter (Minimum) at T6 after 30 min in post anaesthesia care unit inferior venacava diameter (minimum) meaurement at T6
Mean Blood Pressure at T3 30 minutes after induction Mean blood pressure measurement at T3
Heart Rate at T3 30 minutes after induction heart rate monitoring at T3
Heart Rate at T6 post operative period after 30 min in post anaesthesia care unit heart rate monitoring at T6
Systolic Blood Pressure at T2 15 min after induction systolic blood pressure measurement at T2
Systolic Blood Pressure at T3 30 min after induction systolic blood pressure measurement at T3
Diastolic Blood Pressure at T5 120 minutes after induction Diastolic blood pressure measurement at T5
Diastolic Blood Pressure at T6 post induction 30 min in post anaesthesia care unit Diastolic blood pressure measurement at T6
Femoral Vein Velocity Variance 15 minutes pre induction to 30 minutes in post anaesthesia care unit the variance in femoral vein velocity was calculated by subtracting the femoral vein velocity pre induction from femoral vein velocity 15 min after induction divided by mean of the two values in percentage
Femoral Artery Velocity at T2 15 minutes after induction Femoral artery velocity measurement at T2
Heart Rate at T5 120 minutes after induction heart rate monitoring at T5
Systolic Blood Pressure at T0 15 min before induction systolic blood pressure measurement at T0
Systolic Blood Pressure at T5 120 min after induction systolic blood pressure measurement at T5
Systolic Blood Pressure at T6 post operative period 30 min in post asnaesthesia care unit systolic blood pressure measurement at T6
Diastolic Blood Presure at T0 15 minutes before induction Diastolic blood pressure measurement at T0
Diastolic Blood Pressure at T4 60 minutes after induction Diastolic blood pressure measurement at T4
Mean Blood Pressure at T5 120 minutes after induction Mean blood pressure measurement at T5
Mean Blood Pressure at T6 post operative 30 min in post anaesthesia care unit Mean blood pressure measurement at T6
Femoral Vein Velocity at T2 15 minutes after induction Femoral vein velocity measurement at T2
Femoral Artery Velocity at T6 after 30 minutes in post anaesthesia care unit Femoral artery velocity measurement at T6
Inferior Venacava Diameter (Maximum) at T2 15 min after induction inferior venacava diameter (maximum) meaurement at T2
Inferior Venacava Diameter (Minimum) at T2 15 min after induction inferior venacava diameter (minimum) meaurement at T2
Inferior Venacava Diameter Distensibility Index at T2 15 min after induction the inferior venacava distensibility index for post induction mechanically ventilated patients. It was calculated by dividing the difference of maximum inferior vena cava diameter and minimum inferior vena cava diameter by minimum inferior vena cava diameters multiplied by 100 .
FLUID REQUIREMENT (Cumulative) operative period fluid requirement (cumulative) during the operative period.
Blood Loss During Operation During operating procedure Total blood loss during operation
Femoral Artery Velocity at T0 15 minutes pre induction Femoral artery velocity measurement at T0
Inferior Venacava Diameter (Maximum) at T0 15 min pre induction inferior venacava diameter (maximum) meaurement at T0
Inferior Venacava Diameter (Maximum) at T6 after 30 min in post anaesthesia care unit inferior venacava diameter (maximum) meaurement at T6
Inferior Venacava Diameter Collapsibility Index at T0 15 min pre induction the collapsibility index was calculated by dividing the difference of maximum inferior vena cava diameter and minimum inferior vena cava diameter by mean of the two diameters multiplied by 100.This was done for pre induction spontaneously breathing patients
Inferior Venacava Diameter Collapsibility Index at T6 after 30 minutes in post anaesthesia care unit the collapsibility index was calculated by dividing the difference of maximum inferior vena cava diameter and minimum inferior vena cava diameter by mean of the two diameters multiplied by 100.This was done for pre induction spontaneously breathing patients
- Secondary Outcome Measures
Name Time Method