Quantitative Differences of Proteins in Blood According to Amyloid PET / CT Positive Status in Patients with Dementia

Not Applicable

Recruiting

• Conditions: Mental and behavioral disorders

• Registration Number: KCT0004467
• Lead Sponsor: Yonsei University Health System, Severance Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 16 December 2019

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 167

Inclusion Criteria

1) Adults over 40
2) Patients who are taking amyloid PET / CT due to neurologic dementia specialist suspected of cognitive decline worse than MCI.

Exclusion Criteria

1) When it is difficult to cooperate with interview and self-question (literacy, hearing impairment, speech disorder)
2) Patients who cannot consent through the patient or guardian
3) Patients with a medical condition that cannot undergo PET test
History of neurological / psychiatric disorders (territorial cerebral infarction, severe head trauma, brain surgery, intracranial hematoma with permanent brain lesion, major affective disorder, schizophrenia, or schizo-affective disorder)
5) If patients are undergoing radiation therapy or are undergoing radiation exposure in other clinical studies.

Study & Design

• Study Type: Observational Study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Comparison of target protein difference between positive and negative patients

Secondary Outcome Measures

Name	Time	Method
Analyzing whether the amount of target protein reflects severity of dementia