Blood protein level fluctuations
- Conditions
- Neurological diseases10029305
- Registration Number
- NL-OMON55257
- Lead Sponsor
- Amsterdam UMC
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 32
- Mentally competent adults > 18 years, who are member of Hersenonderzoek.nl.
Adults are included when they fill out that they do not have cognitive
complains or when they report they have ongoing Alzheimer*s disease on their
question form
- Mentally competent adults > 18 years, who are participants of the Amsterdam
Dementia Cohort and have evidence of ongoing Alzheimer*s disease. Evidence of
ongoing Alzheimer*s disease is screened using cerebrospinal fluid
amyloid-beta42 levels or using an amyloid PET scan that are available through
the Amsterdam Dementia Cohort database.
People with contra-indications for venipuncture. People aged <18 or people that
are mentally incompetent, due to e.g. a degenerative brain disease.
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Blood material will be processed and concentrations of the protein of interest<br /><br>will be measured. Intra-individual fluctuations om the protein concentration in<br /><br>blood over time will be evaluated.</p><br>
- Secondary Outcome Measures
Name Time Method <p>n.v.t.</p><br>