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Clinical Trials/NCT01974739
NCT01974739
Completed
Not Applicable

Hypernatraemia and Diuretics in Intensive Care Patients

Medical Centre Leeuwarden1 site in 1 country50 target enrollmentSeptember 2013
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ConditionsHypernatraemia
InterventionsHydrochloorthiazideplacebo
DrugsHydrochloorthiazideplacebo

Overview

Phase
Not Applicable
Intervention
Hydrochloorthiazide
Conditions
Hypernatraemia
Sponsor
Medical Centre Leeuwarden
Enrollment
50
Locations
1
Primary Endpoint
sodium level
Status
Completed
Last Updated
10 years ago
OverviewInvestigatorsEligibility CriteriaArms & InterventionsOutcomesSitesSimilar Trials

Overview

Brief Summary

Acquired hypernatremia appears to be associated with mortallity in ICU. To reduce hypernatremia and shorten the time of hypernatremia, we investigate the effect of hydrochloorthiazide compared to a placebo

Registry
clinicaltrials.gov
Start Date
September 2013
End Date
May 2015
Last Updated
10 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Sponsor
Medical Centre Leeuwarden
Responsible Party
Principal Investigator
Principal Investigator

E.C. Boerma

MD PhD

Medical Centre Leeuwarden

Eligibility Criteria

Inclusion Criteria

  • •sodium \> 142

Exclusion Criteria

  • •no informed consent

Arms & Interventions

hydrochloorthiazide

once a day 25 mg

Intervention: Hydrochloorthiazide

placebo

once a day placebo

Intervention: placebo

Outcomes

Primary Outcomes

sodium level

Time Frame: 7 days

a decrease of 5 mmol/L sodium in plama

Secondary Outcomes

  • time hypernatraemia(7 days)

Study Sites (1)

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