Dexmedetomidine Versus Propofol Sedation in Flexible Bronchoscopy: A Randomized Controlled Trial
- Registration Number
- NCT04211298
- Lead Sponsor
- Rabin Medical Center
- Brief Summary
The study will evaluate clinical outcomes during bronchoscopy procedures with dexmedetomidine in comparison to propofol.
The clinical outcomes that will be evaluated are: oxygen saturation, transcutaneous Pco2, blood pressure and complications
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
- All patients in the age group 18 to 70 years requiring flexible bronchoscopic evaluation of the airway in the Pulmonary institute at Rabin medical center
Exclusion Criteria
- known or suspected allergy to any of the study drugs, seizure disorder, renal (with serum creatinine > 2 mg/dL) or hepatic impairment (elevated liver enzymes > 2 times normal), haemodynamic instability (bradycardia with HR < 50 bpm or hypotension with SBP < 90 mmHg), or seriously ill patients with American Society of Anesthesiologists' physical status above III
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Propofol Propofol Propofol will be used for sedation during bronchoscopy Dexmedetomidine Dexmedetomidine Dexmedetomidine will be used for sedation during bronchoscopy
- Primary Outcome Measures
Name Time Method number of de-saturation events During the procedure Number of events during bronchoscopy when saturation level decreased under 90%
Oxygen saturation time < 90% During the procedure Total time during the procedure that the oxygen saturation was under 90%
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Rabin Medical Center
🇮🇱Petach Tikva, Israel