The Relationship Between Optic Nerve Sheath Diameter and Postoperative Delirium in Open Heart Surgery
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- Incidence of delirium after open heart surgery
研究概览
简要总结
Although the incidence of delirium after cardiac surgery is high, it is not sufficiently recognized. The long-term effects of delirium are likely to be underestimated. In this study, the investigators aimed to examine the relationship between optic nerve sheath diameter and postoperative delirium in open hearth surgery.
详细描述
Postoperative delirium is characterized by widespread brain involvement and its incidence is between 6% and 30%. It appears twice as often after cardiac and vascular surgery than other types of surgery. The correlation between optic nerve sheath diameter (ONSD) and invasive intracranial pressure measurement is excellent. ONSD reduction has the potential to indicate intracranial hypoperfusion causing delirium. In this observational study, patients aged 18 years and over who will undergo open heart surgery will be examined. ONSD will be measured using ultrasound five times in the perioperative period (t0: pre-induction, t1: post-induction, t2: onset of cardiopulmonary bypass (CPB), t3: post-CPB, and t4: post-ICU admission). The Confusion Assessment Method for the ICU (CAM-ICU) test will be used to examine delirium in the ICU. Whether the change in ONSD is an independent risk factor for delirium will be evaluated.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 90 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •≥18 year old
- •Elective open heart surgery
排除标准
- •psychiatric illness
- •neurological disease
- •ophthalmic disease
- •previous eye surgery
- •perioperative cerebrovascular disease
- •need for postoperative intraaortic balloon or extracorporeal support system
结局指标
主要结局
Incidence of delirium after open heart surgery
时间窗: 6 months
Using the CAM-ICU test for delirium definition
The relationship between ONSD and postoperative delirium in cardiac surgery
时间窗: 6 months
Peroperatively measured ONSD will be compared with the development of postoperative delirium.
次要结局
未报告次要终点
研究者
Aynur Kaynar
principle investigator
Samsun University
