跳至主要内容
临床试验/NCT05942183
NCT05942183已完成不适用

The Relationship Between Optic Nerve Sheath Diameter and Postoperative Delirium in Open Heart Surgery

Samsun University1 个研究点 分布在 1 个国家目标入组 90 人开始时间: 2023年8月7日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
90
试验地点
1
主要终点
Incidence of delirium after open heart surgery

研究概览

简要总结

Although the incidence of delirium after cardiac surgery is high, it is not sufficiently recognized. The long-term effects of delirium are likely to be underestimated. In this study, the investigators aimed to examine the relationship between optic nerve sheath diameter and postoperative delirium in open hearth surgery.

详细描述

Postoperative delirium is characterized by widespread brain involvement and its incidence is between 6% and 30%. It appears twice as often after cardiac and vascular surgery than other types of surgery. The correlation between optic nerve sheath diameter (ONSD) and invasive intracranial pressure measurement is excellent. ONSD reduction has the potential to indicate intracranial hypoperfusion causing delirium. In this observational study, patients aged 18 years and over who will undergo open heart surgery will be examined. ONSD will be measured using ultrasound five times in the perioperative period (t0: pre-induction, t1: post-induction, t2: onset of cardiopulmonary bypass (CPB), t3: post-CPB, and t4: post-ICU admission). The Confusion Assessment Method for the ICU (CAM-ICU) test will be used to examine delirium in the ICU. Whether the change in ONSD is an independent risk factor for delirium will be evaluated.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 90 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • ≥18 year old
  • Elective open heart surgery

排除标准

  • psychiatric illness
  • neurological disease
  • ophthalmic disease
  • previous eye surgery
  • perioperative cerebrovascular disease
  • need for postoperative intraaortic balloon or extracorporeal support system

结局指标

主要结局

Incidence of delirium after open heart surgery

时间窗: 6 months

Using the CAM-ICU test for delirium definition

The relationship between ONSD and postoperative delirium in cardiac surgery

时间窗: 6 months

Peroperatively measured ONSD will be compared with the development of postoperative delirium.

次要结局

未报告次要终点

研究者

发起方
Samsun University
申办方类型
Other
责任方
Principal Investigator
主要研究者

Aynur Kaynar

principle investigator

Samsun University

研究点 (1)

Loading locations...

相似试验