The bioavailability of anthocyanin after consuming a single dose of red kiwifruit and their effects on innate immunity in healthy individuals.

Not Applicable

• Conditions: utrient absorption; Innate immunity; Nutrient absorption; Metabolic and Endocrine - Normal metabolism and endocrine development and function; Inflammatory and Immune System - Normal development and function of the immune system

• Registration Number: ACTRN12621000302853
• Lead Sponsor: Dr. Dominic Lomiwes

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2021-03-18
• Last Update Posted: 22 March 2021

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 12

Inclusion Criteria

Healthy individuals (male or female) 18 – 55 years who are able to provide written consent to participate in this study will be selected from this study.

Exclusion Criteria

Participants will be excluded if they are unwilling to unable to provide written consent or comply with the study procedures. Participants will also be excluded if they have known hypersensitivity or intolerance to kiwifruit or kiwifruit derived products. In addition, participants will be excluded if they are pregnant, planning to get pregnant in the immediate future or have any of the following conditions: (i) blood borne diseases (e.g. hepatitis), (ii) recent bacterial or viral illness or (iii) are taking medication that affects the properties of blood (e.g. blood clotting).

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The concentration of anthocyanins (and their metabolites) will be measured in blood plasma samples collected from all participants at the same timepoints on all trial days.[This will be measured from blood samples collected at 0, 1, 2, 4 and 6 hours after treatment consumption during each trial day using validated in-house high performance liquid chromatography (HPLC) methods.]