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The Use of Intensive Care in Critically Ill Cancer Haematological Patients: "TRIAL-OH"

Completed
Conditions
Hematological Malignancies
Registration Number
NCT01172132
Lead Sponsor
Assistance Publique - H么pitaux de Paris
Brief Summary

The purpose of this study is to determine:

* Condition of intensive care unit (ICU) admission in patients with haematological malignancies.

* ICU hospital and up to one year mortality.

* Assessment of post ICU burden and health related quality at 90-d and 1 year.

Detailed Description

1. To identify prognostic factors of short and medium term mortality, by underlining the respective weights of organ dysfunction and characteristics of underlined malignancy

2. Evaluate the health related quality of life of intensive care survivors(SF36)

3. Impact of intensive care on families burden (HADS, IES).

4. Assess clinicians' satisfaction ( intensivists, haematologists and intensive care nurses) in relation to medical decision-making.

5. Establish the relevance of antifungal treatments.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
1011
Inclusion Criteria
  • Hematological malignancies
  • hospitalization in ICU
  • age >= 18 years
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Exclusion Criteria
  • Patients who have already participated to TRIAL-OH
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Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Survival status at one year1 year

survival status (alive or death) at one year

Secondary Outcome Measures
NameTimeMethod
Survival statusday 90
ICU mortality1 week (estimated mean time until ICU discharge)

survival status at ICU discharge

Hospital mortality3 weeks (estimated mean time until Hospital discharge)

survival status at hospital discharge

Health related quality of life of patients and their relativesday 90 and 1 year

Trial Locations

Locations (1)

H么pital Saint-Louis, AP-HP

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Paris, France

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