Healing Assessment of Osseous Defects After Surgical Removal of Periapical Lesions
- Conditions
- Effects of the Elements
- Interventions
- Procedure: surgery
- Registration Number
- NCT05100615
- Lead Sponsor
- Minia University
- Brief Summary
recruited patients with periapical lesions will be divided into three groups and surgically treated with three types of bone graft (hydroxyappatite, nanohydroxyappatite and PRF WITH NANOHYDROXTAPPATITE) and then evaluated for month, three months and six months for the healing of periapical bone
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 24
- The patient will be in range of 20-45 years of age at the time of treatment, having periapical lesions starting from 5mm or more in diameter related to failed endodontically treated single canaled teeth.
- Any systemic debilitating disease such as:
Diabetes mellitus, renal disease, Liver disease or liver failure, Rheumatoid arthritis, Neoplastic disease or its treatment, chronic corticosteroid therapy, chronic hepatitis B or C , History of hepatitis A, pregnant females.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description hydroxyappatite surgery hydroxyapatite powder used for enhancement of bone regeneration PRF with nanohydroxyapatite surgery platelet rich fibrin mixed with nanohydroxyapatite used for enhancement of bone regeneration nanohydroxyapatite surgery nanohydroxyapatite powder used for enhancement of bone regeneration
- Primary Outcome Measures
Name Time Method healing of periapical lesion interappointment at 1 month, 3 months and 6 months change in size of bony defect
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Amira mohammed fathy Elkholly
🇪🇬Cairo, Egypt