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Healing Assessment of Osseous Defects After Surgical Removal of Periapical Lesions

Not Applicable
Conditions
Effects of the Elements
Interventions
Procedure: surgery
Registration Number
NCT05100615
Lead Sponsor
Minia University
Brief Summary

recruited patients with periapical lesions will be divided into three groups and surgically treated with three types of bone graft (hydroxyappatite, nanohydroxyappatite and PRF WITH NANOHYDROXTAPPATITE) and then evaluated for month, three months and six months for the healing of periapical bone

Detailed Description

Not available

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
24
Inclusion Criteria
  • The patient will be in range of 20-45 years of age at the time of treatment, having periapical lesions starting from 5mm or more in diameter related to failed endodontically treated single canaled teeth.
Exclusion Criteria
  • Any systemic debilitating disease such as:

Diabetes mellitus, renal disease, Liver disease or liver failure, Rheumatoid arthritis, Neoplastic disease or its treatment, chronic corticosteroid therapy, chronic hepatitis B or C , History of hepatitis A, pregnant females.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
hydroxyappatitesurgeryhydroxyapatite powder used for enhancement of bone regeneration
PRF with nanohydroxyapatitesurgeryplatelet rich fibrin mixed with nanohydroxyapatite used for enhancement of bone regeneration
nanohydroxyapatitesurgerynanohydroxyapatite powder used for enhancement of bone regeneration
Primary Outcome Measures
NameTimeMethod
healing of periapical lesioninterappointment at 1 month, 3 months and 6 months

change in size of bony defect

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Amira mohammed fathy Elkholly

🇪🇬

Cairo, Egypt

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