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Effects of Vasodilators on Renal Function and Neuroholmonal Activation in Patients With Acute Pulmonary Edema

Not Applicable
Conditions
Acute Cardiogenic Pulmonary Edema
Registration Number
JPRN-UMIN000002905
Lead Sponsor
Cardiovascular Division, Hyogo College of Medicine
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow-up complete
Sex
All
Target Recruitment
60
Inclusion Criteria

Not provided

Exclusion Criteria

1)Systolic blood pressure <100mmHg 2)Patients on hemodialysis 3)Patients with acute coronary syndrome 4)Patients with a history of hypersensitivity to any of the components of the product 5)Patients who are judged by the principal investigator to be ineligible for enrollment in the study

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Change in serum creatinine, BUN and cystatin C levels from the admission value to discharge and/or day 7 of hospitalization
Secondary Outcome Measures
NameTimeMethod
Change in serum neuroholmonal factor (catecholamine, renin, angiotensin II, aldosterone and vasopressin) levels before and at 15, 30, 60, and 180 minutes after administration of vasodilators
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