HFNC for Induction During Bariatric Surgery Patients.

Not Applicable

Completed

• Conditions: Lung Collapse
• Interventions: Procedure: Standard group; Procedure: HFNC group

• Registration Number: NCT03155711
• Lead Sponsor: Fundación para la Investigación del Hospital Clínico de Valencia

Brief Summary

This study aims to compared the effects of high flow nasal during the induction and during the weaning of anesthesia on intraoperative and postoperative oxygenation and postoperative atelectasis in obese patients undergoing bariatric surgery versus the standard of care, which consists in supplemental oxygen with face mask (Venturi mask).

Detailed Description

Not available

Study Timeline

• Study Start: 2017-05-05
• Study First Submitted: 2017-05-15
• Study First Submitted QC: 2017-05-15
• Study First Posted: 2017-05-16
• Primary Completion: 2017-09-30
• Study Completion: 2017-12-30
• Status Verified: 2018-02
• Last Update Submitted: 2018-02-23
• Last Update Posted: 2018-02-26

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 64

Inclusion Criteria

• Body mass index > 35 Kg/m2
• Bariatric surgery
• Informed consent signed

Exclusion Criteria

• age <18yr or >80yr
• pregnancy or breast-feeding status
• patients with previous known respiratory disease
• hemodynamic instability at entry (need of vasopressors or ionotropes at entry or a ventricular assist device

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Standard	Standard group	This patients will be managed as usual care. Pre-oxygenation before induction will be performed with supplemental oxygen but without positive pressure. After extubation patients will be oxygenated through a ventury mask.
HFNC	HFNC group	HFNC with a 60 liters per minute flow will be given to the patients before anesthesia induction and before extubation at the end of the surgery

Primary Outcome Measures

Name	Time	Method
Oxygenation	intraoperative	The oxygenation (the ratio of partial pressure of arterial oxygen with inspiratory oxygen fraction, PaO2/FIO2) informs of the percentadge of shunt.

Secondary Outcome Measures

Name	Time	Method
Atelectasis	First 24 postoperative hours	Atelectasis evaluated with X-ray
Oxygenation	First 24 postoperative hours	PaO2/FIO2

Trial Locations

Locations (1)

Hospital clínico universitario; 🇪🇸 Valencia, Spain