Prospective Ultrafast MRI Radiomics for Breast Cancer

Completed

• Conditions: Breast Cancer

• Registration Number: NCT06104189
• Lead Sponsor: Korea University Ansan Hospital

Brief Summary

The goal of this prospective study is to investigate the performance of ultrafast MRI radiomics in classifying histological factors and subtypes of breast cancer compared with standard MRI among radiologists with varying experience. The written informed consent was obtained from all participant. We extracted 1618 radiomic features from ultrafast and standard contrast-enhanced MRI before treatment. Classification of hormonal receptors, human epidermal growth factor receptor 2, and Ki67 status and subtypes was evaluated using the area under the receiver-operating characteristic curve (AUC) with the DeLong test.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-10-01
• Primary Completion: 2022-11-30
• Study Completion: 2023-08-31
• Status Verified: 2023-10
• Study First Submitted: 2023-10-23
• Study First Submitted QC: 2023-10-23
• Last Update Submitted: 2023-10-23
• Study First Posted: 2023-10-27
• Last Update Posted: 2023-10-27

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 225

Inclusion Criteria

• Diagnosed with invasive breast cancer

Exclusion Criteria

• Diagnosed with other cancer

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The signal intensity of MRI according to histological factors and subtypes of breast cancer	Baseline, pre-surgery	Quantitative image values obtained from ultrafast MRI show similar performance in classifying histological factors and subtypes compared with standard MRI.

Trial Locations

Locations (1)

Bo Kyoung Seo; 🇰🇷 Ansan, Korea, Republic of