Comparison between the effect of injecting 2% lignocaine inside the trachea or intravenous in reducing blood pressure and heart rate during visualisation of larynx and insertion of endotracheal tube inside the trachea
Phase 4
- Conditions
- Health Condition 1: R098- Other specified symptoms and signsinvolving the circulatory and respiratory systems
- Registration Number
- CTRI/2023/06/054125
- Lead Sponsor
- Dr Monotosh Pramanik
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
a)American Society of Anesthesiologists (ASA) I-II patients
b)Aged between 18–60 years of both sexes
c)Elective surgical cases under general anesthesia who will require direct laryngoscopy and endotracheal intubation
d)Mallampati score I & II
e)Single-attempt oral intubation
Exclusion Criteria
a)Patient refusal and patients who are unable to give valid consent
b)Pregnant patients
c)Known hypersensitivity to lignocaine
d)Anticipated difficult airway
e)Video laryngoscope-assisted intubation
f)Patients with restricted neck mobility
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare heart rate & blood pressure following direct laryngoscopy & endotracheal intubation in patients receiving 2 percent lignocaine, 1.5 mg/kg via transtracheal & intravenous route respectively.Timepoint: At induction of general anaesthesia, Heart rate and blood pressure will be noted just prior to intubation, immediately after intubation & then at 1, 3, & 5 minutes post intubation.
- Secondary Outcome Measures
Name Time Method To note the incidence of postoperative sore throat in both groups.Timepoint: In the recovery room at arrival & after 24 hrs