Colchicine in myocardial infarctio

Phase 3

Recruiting

• Conditions: Condition 1: ST-elevation myocardial infarction. Condition 2: Cardiac arrhythmia.; ST elevation (STEMI) and non-ST elevation (NSTEMI) myocardial infarction; Other cardiac arrhythmias

• Registration Number: IRCT20220723055534N1
• Lead Sponsor: Qazvin University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 1 May 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 154

Inclusion Criteria

Patients with STEMI that are candidates for PPCI

Exclusion Criteria

Patients who previously used Colchicine or Prednisolone for any reason
Contraindications of Colchicine, including sensitivity to Colchicine, kidney failure (GFR < 10), liver failure (AST - ALT above 5 times normal) and definite history of serious liver diseases (such as hepatitis, hemochromatosis, Wilson's disease, cirrhosis)
Drugs that interact with risk X with colchicine

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The incidence of cardiac arrhythmia. Timepoint: The first day after the occurrence of STEMI. Method of measurement: Checking the rhythm recorded in the 24-hour monitor of the patient.;Cardiac arrhythmia type in the first 24 hours after PPCI. Timepoint: The first day after the occurrence of STEMI. Method of measurement: Checking the rhythm recorded in the 24-hour monitor of the patient.;Comparison of initial and final TIMI of involved vessels. Timepoint: At the beginning and end of coronary angiography. Method of measurement: Based on the standard specified in Branwald's cardiology book, the division is done.