The effectiveness of xylocaine spray in upper gastrointestinal endoscopy

Phase 4

Completed

• Conditions: aspiration pneumonia; methemoglobinemia; anaphylaxis; Anaesthesiology - Anaesthetics; Oral and Gastrointestinal - Other diseases of the mouth, teeth, oesophagus, digestive system including liver and colon

• Registration Number: ACTRN12611000143921
• Lead Sponsor: Chang Gung Memorial Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2011-02-08
• Study Completion: 2011-12-10
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 129

Inclusion Criteria

1. All participants who sign the consent and agreement form
2. All participants who are admitted for upper gastrointestinal endoscopy under general anesthesia with total intravenous anesthesia
3. All participants who are between the age of 20 and 69

Exclusion Criteria

1. young age <20 years; old age >69 years
2. participants who are reported to have allergic reaction to the anesthetic agents used in the study (lidocaine)
3. pregnant women or who are breastfeeding
4. participants who are deemed to have significant higher risk if enrolled in the study (eg severe obstructive sleep apnea)

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The overall ease of the endoscopy assessed by endoscopists via rating scales.<br>Rating scales are used to assess by endoscopists. The parameters include patients' ability to follow verbal command, show somatic response after anesthesia, have any coughs, hiccups, or gag reflex on esophageal intubation and also the overall ease of esophageal intubation and satification of the procedure by endoscopists.[at the end of the endoscopy]

Secondary Outcome Measures

Name	Time	Method
Hemodynamic changes during endoscopy (eg heart rate, non-invasive blood pressure, oxygen saturation on 3L oxygen nasal prong, BIS index) and the requirement of airway maneuver[The hemodynamic values (HR, BP, BIS, SpO2) are recorded on arrival, then every 2 min afterwards during endoscopy and again on departure.]