Abscisic Acid Effects on Glucose Homeostasis and Insulin Sensitivity
Phase 2
Active, not recruiting
- Conditions
- Pre Diabetes
- Registration Number
- NCT04722354
- Lead Sponsor
- AdventHealth Translational Research Institute
- Brief Summary
The purpose of this study is to determine the effects of oral abscisic acid (ABA) on glucose metabolism in subjects with defined prediabetes.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ACTIVE_NOT_RECRUITING
- Sex
- All
- Target Recruitment
- 48
Inclusion Criteria
Not provided
Exclusion Criteria
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Primary Outcome Measures
Name Time Method Insulin sensitivity 4-6 hours Insulin sensitivity will be measured using hyperinsulinic euglycemic clamp
Monitoring adverse events 10 weeks Adverse events will be monitored at each visit throughout the duration of the study.
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms does abscisic acid (ABA) influence in glucose homeostasis and insulin sensitivity?
How does oral abscisic acid (ABA) compare to metformin in improving insulin sensitivity in prediabetic patients?
Are there specific biomarkers that correlate with ABA-induced improvements in glucose metabolism in prediabetes?
What are the potential adverse events associated with abscisic acid (ABA) in phase 2 trials for prediabetic populations?
What combination therapies with abscisic acid (ABA) are being explored for enhancing glucose regulation in prediabetes?
Trial Locations
- Locations (1)
AdventHealth Translational Research Institute
🇺🇸Orlando, Florida, United States
AdventHealth Translational Research Institute🇺🇸Orlando, Florida, United States