Pelvic versus peripheral steroid levels in postmenopausal patients with and without endometrial hyperplasia or carcinoma.

Completed

• Conditions: abnormalities of the uterine mucosa; endometrial abnormalities; 10018515; 10038594

• Registration Number: NL-OMON34624
• Lead Sponsor: Gynaecologie & obstetrie

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 30

Inclusion Criteria

All postmenopausal women planned to undergo an abdominal hysterectomy with bilateral salpingo-oophorectomy. Patients must meet the following criteria:
- have at least one ovary before entering the study
- are willing to consent to the collection and storage of blood for this study
- signed informed consent form according to national/local regulations

Exclusion Criteria

- Patients with known abnormalities in the steroid metabolism
- Patients who receive hormone replacement therapy
- Patients with any disorder making it impossible to give informed consent

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Serum estrogen, progesterone and androgen levels will be measured in the<br /><br>bloodsamples, with a standard and validated radioimmunoassay (RIA) as used by<br /><br>the clinical chemistry lab of the MUMC. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>n/a</p><br>