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临床试验/NCT03534427
NCT03534427已完成不适用

The Effects of a 12-Week Jump Rope Exercise Training Program on Arterial Stiffness, Vasodilating and Vasoconstricting Factors, Inflammatory Markers, and Body Composition in Prehypertensive Adolescent Girls

Pusan National University0 个研究点目标入组 40 人开始时间: 2011年6月5日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
40
主要终点
Nitrate/Nitrite Levels

研究概览

简要总结

The purpose of this study was to examine the impact of a 12-week jump rope exercise program on blood pressure, arterial stiffness, vasodilating and vasoconstricting factors, inflammatory markers, and body composition in prehypertensive adolescent girls. Forty prehypertensive adolescent girls participated in this study. The girls were randomly divided into the jump rope exercise intervention group (EX, n=20) and control group (CON, n=20). The EX group performed a jump rope training program at 40-70% of their heart rate reserve (HRR) 5 days/week for 12 weeks (sessions 50 minutes in duration). The CON group did not participate in any structured or unstructured exercise protocol. Blood pressure, arterial stiffness, plasma nitrate/nitrite levels, endothelin-1, C-reactive protein, and body composition were measured before and after the 12-weeks study.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Health Services Research
盲法
None

入排标准

年龄范围
14 Years 至 16 Years(Child)
性别
Female
接受健康志愿者

入选标准

  • prehypertensive
  • sedentary (no regular exercise training or physical activity within the last year)
  • no weight loss diet during the last six months

排除标准

  • pregnancy
  • chronic disease
  • daily medication use (including antioxidants and weight loss supplements)

结局指标

主要结局

Nitrate/Nitrite Levels

时间窗: 12 weeks

Nitrate and nitrite levels were assayed using a Griess assay kit.

Body Mass

时间窗: 12 weeks

Body mass was measured to nearest 0.1 kg.

Body Fat

时间窗: 12 weeks

Percent body fat (%) was determined using a bioelectrical impedance-meter.

Diastolic Blood Pressure

时间窗: 12 weeks

Waist Circumference

时间窗: 12 weeks

Waist circumference was measured at midpoint between the lower rib and the iliac crest at the end of a normal expiration using a tape measure.

C-reactive Protein

时间窗: 12 weeks

C-reactive protein was assessed using an enzyme immunoassay assay kit

Systolic Blood Pressure

时间窗: 12 weeks

Blood pressure was measured in duplicate using an automated sphygmomanometer. The average of the two was recorded as the resting blood pressure.

Lean Body Mass

时间窗: 12 weeks

Lean body mass (kg) was determined using a bioelectrical impedance-meter.

Arterial Stiffness

时间窗: 12 weeks

Arterial stiffness was measured as measurement of brachial to ankle pulse-wave velocity. This indicates peripheral arterial stiffness, as it measures how quickly a pulse wave propagates from one point to another.

Endothelin-1

时间窗: 12 weeks

Levels of Endothelin-1 in blood were measured by Endothelin-1 enzyme immunoassay kit.

Height

时间窗: 12 weeks

Height was measured to nearest 1 cm.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Won-mok son

Principal Investigator

Pusan National University

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