The influence of peroperative dobutamine infusion on the blood flow of the DIEP-flap

Completed

• Conditions: breast reconstruction with own tissue; DIEP-flap reconstruction; 10062915; 10006291; 10006232

• Registration Number: NL-OMON38526
• Lead Sponsor: Orbis Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 11 June 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 60

Inclusion Criteria

- women
- age between 30 and 65 years old
- breast carcinoma in the history
- mastectomy in the history
- planned secondary reconstruction by means of a DIEP-flap

Exclusion Criteria

- cardiac history (i.e. atrial fibrillation)
- clotting disorders (deep venous thrombosis or pulmonary embolus in the history)
- smoking
- allergic reaction to dobutamine or bisulfate

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Increase in microcirculatory blood flow after dobutamine infusion and measured<br /><br>by means of laser Doppler flowmetry. </p><br>