Effect of analgesia-sedation protocol on pain, agitation and cardiovascular response of trauma

Phase 3

Recruiting

Conditions: trauma.
Acute pain due to trauma
G89.11

Registration Number: IRCT20150919024080N17

Lead Sponsor: Khoram-Abad University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: All

Target Recruitment: 84

Inclusion Criteria

Trauma patients (abdominal, chest, orthopedics trauma, and etc.)
Patients need a ventilator with a minimum duration of 24 hours connected to the ventilator.
Patients separated from the ventilator The minimum duration of separation from the ventilator is 24 hours.
Willingness to participate in the study.
Being able to self-report pain or express pain behaviors.
level of consciousness equal and above 7
The minimum length of hospital stay in the ICU should be 48 hours.
No pregnancy.
No coagulation disorders

Exclusion Criteria

Transfer to home and using palliative care unit (end of life).
Plant life, quadriplegia and the need for continuous infusion of nerve blockers and inhaled prostacyclins.
Deep sedation to quit alcohol.
Need for continuous infusion of sedative or analgesic for more than 24 hours.
Patients with permanent brain injury admitted to neurosurgery wards.
Deep sedation for treatment of active seizures.
Patients in the final stage of kidney and liver failure.
Cardiac arrest.
Neurovascular injury, burns, ear, nose and throat surgeries, maxillofacial surgery, or plastic surgery to place a flap on the head or neck.

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pain intensity in trauma patients in special surgical wards. Timepoint: Twice a day at 8-10 and 18-16 hours for a maximum of 4 days. Method of measurement: Behavioral Pain Scale BPS-NI, BPS, NRS Pain Numerical Scale.;Severity of restlessness in trauma patients in surgical wards. Timepoint: Twice a day at 8-10 and 18-16 hours for a maximum of 4 days. Method of measurement: Richmond Scale (RASS).;Incidence of delirium in trauma patients in special surgical wards. Timepoint: Once a day for 18-16 hours for a maximum of 4 days. Method of measurement: CAM-ICU scale.

Secondary Outcome Measures

Name	Time	Method
Cardiovascular response of trauma patients in surgical special wards. Timepoint: Before and after each drug intervention. Method of measurement: Blood pressure with Blood pressure monitor and pulse monitoring with cardiac and respiratory monitoring with manual count in one minute.