Is ketamine a useful addition for the management of acute pain in patients where opiates alone have failed to provide adequate analgesia?

Phase 3

• Conditions: Difficult to control acute pain; Emergency medicine - Other emergency care

• Registration Number: ACTRN12615001151527
• Lead Sponsor: Bundaberg Base Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2015-10-29
• Study Completion: 2018-06-04
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Stopped early
• Sex: All
• Target Recruitment: 23

Inclusion Criteria

Patients reporting acute onset of pain of any cause except cardiac origin but including cases where the cause is unknown. A verbal numeric rating scale pain score of greater than or equal to 5 after having received a total intravenous dose of 7.5mg morphine, 100mcg fentanyl or other equipotent opiate.

Exclusion Criteria

Patients whose primary language is other than English
Women who are pregnant
Patients aged <18 years
Patients with intellectual or mental impairment
A patient in whom we are unable to gain venous access
Patients with known chronic kidney disease stage 4 or above
Acute severe respiratory distress
Presenting with presumed cardiac diagnosis
A documented allergy to morphine or ketamine

Study & Design

• Study Type: Interventional
• Study Design: Not specified