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Clinical Trials/TCTR20220525002
TCTR20220525002
Not yet recruiting
Phase 1

Predicting fluid responsiveness by reverse tidal volume challenge in patients undergoing high-risk surgery

Overview

Phase
Phase 1
Intervention
Not specified
Conditions
Patients older than 18 yr who schedule for high-risk surgery with mechanically ventilated during general anesthesia
Sponsor
Faculty of Medicine Ramathibodi Hospital, Mahidol University
Enrollment
50
Status
Not yet recruiting
Last Updated
last year

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
May 25, 2022
End Date
December 31, 2022
Last Updated
last year
Study Type
Interventional
Sex
All

Investigators

Eligibility Criteria

Inclusion Criteria

  • 1\. Adult (age equal to or more than 19 years) patient
  • 2\. High\-risk surgical procedure (expected operative time more than 2 hours and need an invasive arterial pressure monitoring)

Exclusion Criteria

  • 1\. patients with preoperative cardiac arrhythmia, moderate to severe valvular heart disease, preoperative left ventricular ejection fraction \<40%, right ventricular dysfunction, intracardiac shunts
  • 2\. moderate to severe chronic obstructive pulmonary disease, acute lung injury, coexisting open thorax condition
  • 3\. moderate to severe renal or liver disease
  • 4\. preoperative need of inotropes and vasopressor
  • 5\. severe bradycardia
  • 6\. abdominal compartment syndrome
  • 7\. pregnancy
  • 8\. spontaneous breathing
  • 9\. Decline to participate in the study

Outcomes

Primary Outcomes

Not specified

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