Prediction of Fluid Responsiveness by Measuring the Effect of Lung Recruitment Maneuver to Perfusion Index in Mechanically Ventilated Patients During Surgery

Completed

• Conditions: Patients older than 18 yr who scheduled for elective non-laparoscopic surgery; Elective surgery, fluid responsiveness, Perfusion index and recruitment maneuver

• Registration Number: TCTR20201202001
• Lead Sponsor: Faculty of Medicine Ramathibodi Hospital, Mahidol University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2020-12-02
• Study Completion: 2021-04-29
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 32

Inclusion Criteria

Elective surgery
- Equipped with a radial arterial catheter and cardiac output monitor

Exclusion Criteria

-Arrhythmia, preoperative lung disease, left ventricular ejection fraction less than 50%, possible right ventricular dysfunction due to sleep apnea/severe chronic obstructive pulmonary disease/pulmonary hypertension
- Intracranial hypertension, Hemodynamic unstable
- Laparoscopic surgery

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Sensitivity and specificity of PI reduction after RM to predict preload responsiveness within 10-15 minute (after fluid challenge) Perfusion index reduction after recruitment maneuver

Secondary Outcome Measures

Name	Time	Method
Sensitivity and specificity of PVI and PVI change to predict preload responsiveness within 10-15 minute (after fluid challenge) Pleth variability index (PVI)