THE PREDICTION OF FLUID RESPONSIVENESS USING PULSE PRESSURE VARIATION AFTER TIDAL VOLUME CHALLENGE IN POSTOPERATIVE PATIENT WITH LUNG PROTECTIVE VENTILATIO
Not Applicable
- Conditions
- Postoperative acute circulatory faiureTidal volumeShockStroke volume
- Registration Number
- TCTR20190808003
- Lead Sponsor
- Faculty of Medicine, Ramathibodi Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Enrolling by invitation
- Sex
- All
- Target Recruitment
- 15
Inclusion Criteria
1. Postoperative adult patients with intermediate to high risk postoperative pulmonary complications ventilated with low tidal volume ventilation
2. Patients who had postoperative circulatory failure defined as one of the following; MAP < 65 mmHg, SBP < 90 mmHg, SBP decrease more than 40 mmHg from baseline, arterial lactate > 4 mmol/l, urine output < 0.5 ml/kg/hr at least one hour.
3. Patients who already had arterial line in place
Exclusion Criteria
1. Limitation of PPV and SVV use
2. Pregnancy
3. Use of plateau pressure more than 30 cmH2O before inclusion
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The prediction of fluid responsiveness After inclusion The increase of stroke volume after fluid loading
- Secondary Outcome Measures
Name Time Method The cut point of delta pulse pressure variation and stroke volume variation After inclusion The increase of stroke volume after fluid loading