Effect of yoga therapy on cardiac autonomic functions and oxidative stress in subjects at risk of high blood pressure

Active, not recruiting

• Conditions: Prehypertension

• Registration Number: CTRI/2012/09/003017
• Lead Sponsor: Intramural fund JIPMER Pondicherry

Brief Summary

This is a randomized controlled study, the subjects with prehypertension (systolic BP 120-139 mmHg and/or diastolic BP 80-89 mmHg) will be screened in various OPDs & staffs of JIPMER, government officials and also through various screening camps in Pondicherry. After the baseline recording they will be randomized to either lifestyle modification (LSM) group or LSM + yoga group for 12 weeks. The expected primary outcome will be improved resting blood pressure, cardiovagal modulation and oxidative stress parameters. The secondary outcomes will be improved quality of life, physical and mental well-being and cardiovascular risk for next ten years.

Detailed Description

Not available

Study Timeline

• Study Start: 2010-08-30
• Last Update Posted: 2013-03-08

Recruitment & Eligibility

• Status: Closed to Recruitment of Participants
• Sex: Not specified
• Target Recruitment: 204

Inclusion Criteria

SBP : 120 – 139 mmHg and / or DBP : 80 – 89 mmHg Age : 20 – 60 years Gender : both Willing to practice yoga Written informed consent.

Exclusion Criteria

Diabetes mellitus Cardiovascular disease Autonomic failure Renal insufficiency Patients on drug treatment for prehypertension Any physical condition hindering the performance of yoga Subjects already practicing yoga Sports persons, athletes & body builders.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The addition of yoga therapy to standard lifestyle modification approaches confers additional benefits in terms of:	After 12 weeks of intervention
1. Lowering resting blood pressure	After 12 weeks of intervention
2. Increasing overall short-term HRV	After 12 weeks of intervention
3. Indices of oxidative stress	After 12 weeks of intervention

Secondary Outcome Measures

Name	Time	Method
Improvement in,	1. Quality of life

Trial Locations

Locations (1)

Autonomic Lab, Department of Physiology; 🇮🇳 Pondicherry, PONDICHERRY, India

Autonomic Lab, Department of Physiology

🇮🇳Pondicherry, PONDICHERRY, India

Ramkumar Thiyagarajan

Principal investigator

9843666896

ramkumar2211@gmail.com