Effect of yoga therapy on cardiac autonomic functions and oxidative stress in prehypertension subjects: a randomized controlled study
Trial Snapshot
- Phase
- Not Applicable
- Status
- Active, not recruiting
- Sponsor
- Enrollment
- 204
- Locations
- 1
- Primary Endpoint
- The addition of yoga therapy to standard lifestyle modification approaches confers additional benefits in terms of:
Study Overview
Brief Summary
This is a randomized controlled study, the subjects with prehypertension (systolic BP 120-139 mmHg and/or diastolic BP 80-89 mmHg) will be screened in various OPDs & staffs of JIPMER, government officials and also through various screening camps in Pondicherry. After the baseline recording they will be randomized to either lifestyle modification (LSM) group or LSM + yoga group for 12 weeks. The expected primary outcome will be improved resting blood pressure, cardiovagal modulation and oxidative stress parameters. The secondary outcomes will be improved quality of life, physical and mental well-being and cardiovascular risk for next ten years.
Study Design
- Study Type
- Interventional
- Allocation
- Permuted block randomization, variable
- Masking
- Not Applicable
Eligibility Criteria
- Ages
- 20.00 Year(s) to 60.00 Year(s) (—)
Inclusion Criteria
- •SBP : 120 – 139 mmHg and / or DBP : 80 – 89 mmHg Age : 20 – 60 years Gender : both Willing to practice yoga Written informed consent.
Exclusion Criteria
- •Diabetes mellitus Cardiovascular disease Autonomic failure Renal insufficiency Patients on drug treatment for prehypertension Any physical condition hindering the performance of yoga Subjects already practicing yoga Sports persons, athletes & body builders.
Outcomes
Primary Outcomes
The addition of yoga therapy to standard lifestyle modification approaches confers additional benefits in terms of:
Time Frame: After 12 weeks of intervention
1. Lowering resting blood pressure
Time Frame: After 12 weeks of intervention
2. Increasing overall short-term HRV
Time Frame: After 12 weeks of intervention
3. Indices of oxidative stress
Time Frame: After 12 weeks of intervention
Secondary Outcomes
- Improvement in,(1. Quality of life)