ordic Cerebellar Mutism Syndrome Study
Completed
- Conditions
- Cerebellar Mutism Syndrome (of: Posterior Fossa Syndrome)1002921110009720
- Registration Number
- NL-OMON42392
- Lead Sponsor
- Radboud Universitair Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
age < 18 years
patients undergoing surgery for brainstem or cerebellar tumor
Exclusion Criteria
no informed consent
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>To explore the relationship between different surgical methods for the removal<br /><br>of posterior fossa tumours, and relate these to the incidence and clinical<br /><br>course of the CMS (prospective observational study).<br /><br>Hypothesis: Methods that spare the dentate nuclei and their efferents and focus<br /><br>on minimally traumatic techniques lower the risk of developing the CMS by 50%,<br /><br>and lessen its severity and duration by 40% when compared to more invasive<br /><br>tumour removal methods. The risk of getting the CMS is greater after<br /><br>re-operation(s) when compared to primary surgery. </p><br>
- Secondary Outcome Measures
Name Time Method