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Gemcitabine with the standard dose (1000 mg/m2) is equal to low dose (250 mg/m2) with just prolongation of the infusion time in Patients with Advanced Pancreatic cancer

Phase 2
Conditions
Cancer
Registration Number
PACTR201901862142418
Lead Sponsor
South Egypt cancer Institute
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
100
Inclusion Criteria

Patients with advanced pancreatic cancer in males or females with age of 18 years or older, with an Eastern Cooperative Oncology Group (ECOG) performance status of 0 to 2, chemotherapy-naïve, and adequate hematologic, hepatic, and renal functions.

Exclusion Criteria

1.Patient refuses to be enrolled in study.
2.Contraindication to gemcitabine
3.Concurrent anticancer or radiation therapy.
?Start of study therapy must be at 4 weeks after completion of previous anticancer therapy and 2 weeks from the date of last radiation.
4.Use of gemcitabine within the past 3 months with progression.
5.Any psychiatric illness/social situations that would limit compliance with study requirements.
6.Pregnant or nursing women.
7.Synchronous malignancies i.e associated other body cancers.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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